In certain embodiments, the present invention provides a compound of formula I, wherein n is 1, p is 1, q is 1, R 2 is chloro, R 3 is hydrogen, R 4 is hydrogen, Ring A is piperidinyl, piperazinyl, or morpholinyl, and Ring B is [Only registered and activated users can see links. Click Here To Register...] Surgery 138 1018 25, 2005