[Only registered and activated users can see links. Click Here To Register...] The residue was purified by flash silica gel chromatography using an eluent of 0 8 MeOH DCM to give 3S tert butyl 4 6 fluoro 7 2 fluoro 6 hydroxyphenyl 1 4 3 hydroxypropyl 2 isopropylpyridin 3 yl 2 oxo 1, 2 dihydropyrido 2, 3 d pyrimidin 4 yl 3 methylpiperazine 1 carboxylate Int 49b 1
