Although thymocytes from mice of all genotypes were killed at a similar rate when treated with PMA kills in a PUMA dependent manner 24, untreated medium and Ionomycin treated thymocytes from 4 OHT treated Bim, Bim fl fl Vav CreER tg and Bim fl fl Rosa CreER tg mice all showed a marked survival advantage when compared with thymocytes from 4 OHT treated Bim fl fl, Rosa CreER tg and Vav CreER tg mice

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