Cullins control the ubiquitylation of a wide variety of substrates, and form the largest known family of ubiquitin ligase complexes mammals express approximately 70 F box proteins, 30 BC box proteins, 200 BTB proteins, and

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عضویت

In these experiments, cardiac lysates were incubated with a biotinylated acylphosphate ATP derivative that irreversibly transfers biotin to conserved lysine residues in the ATP binding pocket of protein kinases and other ATP binding proteins