The importance of VEGF signaling in TSC and LAM suggests that combination therapies that aim to inhibit mTOR signaling along with disrupting VEGF signaling may be more successful than single agents.

مهمان عزیز شما حق دیدن لینک ها را ندارید برای استفاده از امکانات کامل انجمن عضو شوید

عضویت

Collectively, our results indicate that KLF4 methylation by PRMT5 stabilizes KLF4 by antagonizing VHL- mediated KLF4 ubiquitylation.