Once intracellular, amikacin functions by targeting the decoding A- site located on the 16S rRNA within the bacterial 30S ribosomal subunit, thereby changing the conformation and interfering with the proofreading of base- pairing between mRNA and tRNA leading to mistranslation see Figure 2 6, 11.

مهمان عزیز شما حق دیدن لینک ها را ندارید برای استفاده از امکانات کامل انجمن عضو شوید

عضویت

2010 Apr; 2 2 77- 86.