Missense or truncating mutations in patients with Liddle syndrome alter the carboxyl terminal cytoplasmic tail of the ОІ or Оі subunit in a domain that is important for interactions with the cytoskeletal protein that regulates activity of the ENaC [Only registered and activated users can see links. Click Here To Register...] Diet and exercise are two of the best initial options to restore fertility and alleviate symptoms in obese women with PCOS
