acedono
12-12-2022, 05:28 AM
2 2 methoxyethyl phosphodiester 2 deoxy phosphorothioate 2 O methoxyethyl phosphodiester chimeric oligonucleotides are prepared as per the above procedure for the 2 O methyl chimeric oligonucleotide with the substitution of 2 O methoxyethyl amidites for the 2 O methyl amidites, oxidization with iodine to generate the phosphodiester internucleotide linkages within the wing portions of the chimeric structures and sulfurization utilizing 3, H 1, 2 benzodithiole 3 one 1, 1 dioxide Beaucage Reagent to generate the phosphorothioate internucleotide linkages for the center gap priligy generic ([Only registered and activated users can see links])