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12-02-2022, 10:39 AM
Tamoxifen itself is known to have a relatively weak affinity for the estrogen receptor ER and to undergo extensive primary and secondary metabolism mainly by the CYP2D6 enzyme, forming clinically active metabolites, which include 4 hydroxytamoxifen and endoxifen 4 hydroxytamoxifen and N desmethyltamoxifen stromectol dosage for pinworms ([Only registered and activated users can see links])