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36 37 Unfortunately, our data do not resolve the issue of whether estrogens affect vascular reactivity through endothelium or smooth muscle mediated mechanisms, but this study was not designed to do so buy cialis online canadian pharmacy ([Only registered and activated users can see links]) It has been shown to be as effective as the oral aromatase inhibitor anastrozole in postmenopausal women with advanced breast cancer who have progressed on prior endocrine therapy, principally tamoxifen